Is there anything to be aware of when installing Spire related to Port assignment?
By default, Spire will use Port 10880. That is fine for a standalone installation of the product.
However, if you have an existing BVEssentials installation, then it too is using Port 10880 by default, and there will be a conflict.
You will need to decide which one will remain at 10880, and assign an alternate number, such as 10888 to to the other.
If you know ahead of time that BVE is installed, you could choose when installing Spire to override the default Port number.
Or, you can manually change BVE ahead of time (to 10888 - using the BVEssential Server Manager) and then when you install Spire allow it to continue with it's default (10880).